Phenylpropanoids and polyketides
Medchemexpress LLC Genistin | 529-59-9 | 432.38 | 5 MG
Genistin (Genistine) is an isoflavone from the phytoestrogen family, acting as a potent anti-adipogenic and anti-lipogenic agent. It attenuates cellular growth and promotes apoptotic cell death in breast cancer cells by modulating the ERalpha signaling pathway. It also negatively regulates ERα, down-modulates ER nuclear translocation, and suppresses oncogenic markers in MCF-7 cells.
- Isoflavone from the phytoestrogen family
- Potent anti-adipogenic and anti-lipogenic agent
- Attenuates cellular growth in breast cancer cells
- Promotes apoptotic cell death in breast cancer cells
- Modulates ERalpha signaling pathway
- Negatively regulates ERα
- Down-modulates ER nuclear translocation and DNA binding activity
- Suppresses oncogenic markers in MCF-7 cells
eMolecules Medchem Express / Tesaglitazar / 5mg / 724442389 / HY-17444 / / 251565-85-2 / MFCD07784004 / 408.470 / C20H24O7S
Medchem Express / Tesaglitazar / 5mg / 724442389 / HY-17444 / / 251565-85-2 / MFCD07784004 / 408.470 / C20H24O7S
Selleck Chemical LLC 5-methoxyflavone S4782-25mg
5-methoxyflavone is a novel DNA polymerase-beta inhibitor and neuroprotective agent against beta-amyloid toxicity
Selleck Chemical LLC p-Coumaric Acid S4759-1g
p-Coumaric acid (4-Hydroxycinnamic acid P-Hydroxycinnamic acid 4-Coumaric acid Trans-p-Coumaric acid para-Coumaric Acid) is a hydroxy derivative of cinnamic acid found in a variety of edible plants and is reported to have antioxidant anti-inflammatory and antimicrobial activity
Selleck Chemical LLC Tyrphostin 9 S2895-25mg
Tyrphostin 9 (SF 6847 RG-50872) is firstly designed as an EGFR inhibitor with IC50 of 460 M but is also found to be more potent to PDGFR with IC50 of 0 5 M
Cambridge Isotope Laboratories 4-Hydroxy-3-methoxycinnamic acid (ferulic acid) (1 2 3-13C3 99%) 5 mg
4-Hydroxy-3-methoxycinnamic acid (ferulic acid) (1 2 3-13C3 99%) 5 mg
Cayman Chemical 4-HydroxycoumarIn 500g
A coumarin; inhibits vitamin K1 epoxidation and prothrombin synthesis by 18 and 67%, respectively, in cell-free assays at 6.2 mM; has been used in the synthesis of anticoagulants, as well as antithrombotic, anti-inflammatory, antibacterial, and antifungal agents
Medchemexpress LLC Tyrphostin 25 | 118409-58-8 | MFCD00133900 | 99.0% | 202.17 | C10H6N2O3 | 10 MG
Tyrphostin 25 (AG82) is a small-molecule research compound that selectively inhibits epidermal growth factor receptor (EGFR) tyrosine kinase and acts as a GPR35 agonist. It prevents EGFR autophosphorylation and reduces EGF-induced cell migration in vitro. Supplied as a yellow to brown solid with high analytical purity for laboratory research; for research use only.
- High purity: 99.0%.
- Molecular weight: 202.17 g/mol.
- Chemical formula: C10H6N2O3.
- Physical form: solid, yellow to brown powder.
- Biological activity: EGFR IC50 ≈ 3 μM (A431 cells); GPR35 EC50 ≈ 5.3 μM.
- Storage: powder -20°C (stable for years); in solution -80°C (months).
- SDS available in multiple languages.
- Intended use: for research use only.
Medchemexpress LLC p-Coumaric acid-13C3 | 1261170-80-2 | 167.14 | 1 MG
p-Coumaric acid-13C3 is the 13C-labeled version of p-Coumaric acid. p-Coumaric acid is a prevalent isomer of cinnamic acid, known for its antitumor and anti-mutagenic properties. This compound is intended for research use only and is not sold to patients. Stable heavy isotopes, including carbon, are incorporated into drug molecules primarily as tracers for quantification during drug development. Deuteration, in particular, has gained attention for its potential to influence the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Rutin trihydrate | 250249-75-3 | ≥97.0% | 664.56 | 50 MG
Rutin (Rutoside) trihydrate is a multifunctional natural flavonoid glycoside. It has demonstrated excellent antioxidant, anti-inflammatory, anti-diabetic, and anti-carcinogenic properties. It also exhibits cardioprotective and neuroprotective activities.
- Multifunctional natural flavonoid glycoside
- Excellent antioxidant properties
- Anti-inflammatory properties
- Anti-diabetic properties
- Anti-carcinogenic properties
- Cardioprotective activities
- Neuroprotective activities